Biosimilar參照抗體

在生物藥研發(fā)中，抗體藥物研發(fā)無疑是最受關(guān)注的焦點，是增長最快的細分領(lǐng)域之一，已成為生物藥中最重要的一大品類。在抗體藥物開發(fā)過程中，頭對頭的質(zhì)量可比性研究更是重中之重。通常臨床階段及上市抗體藥分子是大家首選的對標參照。

締碼生物功能活性蛋白表達平臺利用HEK293哺乳動物細胞分泌表達系統(tǒng)，重組表達了眾多熱門靶點的biosimilar參照抗體，便利廣大科研工作者進行相關(guān)開發(fā)過程中的對比研究，同時也可以輔佐驗證靶點蛋白的功能活性。

pages-1 3

產(chǎn)品數(shù)據(jù)展示：

?

活性蛋白檢測

pages-2 4

Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human PD1, mFc-His tagged protein (PME100025) can bind Anti-PD-1 Neutralizing antibody in a linear range of 0.24-6.49 ng/ml.

流式功能檢測對比

pages-3 3

Figure 2. HEK293 cell line transfected with irrelevant protein and human PD1 were surface stained with anti-PD1 neutralizing antibody 1μg/ml (pembrolizumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.

Biosimilar參照抗體列表

SKU:  BME100134P     Target:  KIR2DL2

Application:  Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-LILRB2 (MK-4830) mAb

SKU:  BME100145P     Target:  LILRB2

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100137P     Target:  IL17A

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100133P     Target:  CXCL10

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100132P     Target:  IL20

Application:  Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-FLT1(icrucumab biosimilar) mAb

SKU:  BME100131P     Target:  FLT1

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100130P     Target:  GM-CSF

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100128P     Target:  PSMA

Application:  Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CCL2(carlumab biosimilar) mAb

SKU:  BME100125P     Target:  CCL2

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100112P     Target:  TSLP

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100107P     Target:  DKK1

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100095P     Target:  PCSK9

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100105P     Target:  CCN2

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100129P     Target:  CD73

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100127P      Target:  SSTR2

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100124P     Target:  CD142

Application:  Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-IL9(enokizumab biosimilar) mAb

SKU:  BME100122P     Target:  IL9

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100117P     Target:  IFNAR1

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100116P     Target:  IL1B

Application:  Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CCR8(BMS 986340) mAb

SKU:  BME100115P     Target:  CCR8

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100120P     Target:  C5AR1

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100119P     Target:  NRP1

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100090P     Target:  GDF15

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100114P     Target:  IL22

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100109P     Target:  B7-H5

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100099P     Target:  NOTCH3

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100106P     Target:  AMHR2

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100104P     Target:  M-CSF

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100102P     Target:  CD56

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100101P     Target:  CXCR4

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100100P     Target:  CEACAM6

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100097P     Target:  IL1A

Application:  Flow Cyt

Price: 100 test ￥1360.00