Biosimilar參照抗體

在生物藥研發(fā)中，抗體藥物研發(fā)無疑是最受關注的焦點，是增長最快的細分領域之一，已成為生物藥中最重要的一大品類。在抗體藥物開發(fā)過程中，頭對頭的質量可比性研究更是重中之重。通常臨床階段及上市抗體藥分子是大家首選的對標參照。

締碼生物功能活性蛋白表達平臺利用HEK293哺乳動物細胞分泌表達系統(tǒng)，重組表達了眾多熱門靶點的biosimilar參照抗體，便利廣大科研工作者進行相關開發(fā)過程中的對比研究，同時也可以輔佐驗證靶點蛋白的功能活性。

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產(chǎn)品數(shù)據(jù)展示：

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活性蛋白檢測

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Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human PD1, mFc-His tagged protein (PME100025) can bind Anti-PD-1 Neutralizing antibody in a linear range of 0.24-6.49 ng/ml.

流式功能檢測對比

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Figure 2. HEK293 cell line transfected with irrelevant protein and human PD1 were surface stained with anti-PD1 neutralizing antibody 1μg/ml (pembrolizumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.

Biosimilar參照抗體列表

SKU:  BME100086B     Target:  CCR4

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100084B     Target:  IL7RA

Application:  Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100083B     Target:  GPC3

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

Biosimilar reference antibodies

Biotinylated Anti-CLDN6 (IMAB027) mAb

SKU:  BME100082B     Target:  CLDN6

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100081B     Target:  B7-H2

Application:  Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100078B     Target:  B7H4

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100077B     Target:  SELP

Application:  Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100076B     Target:  CD47

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100073B     Target:  ROR1

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100068B     Target:  DLL3

Application:  ELISA, Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100067B     Target:  GUCY2C

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100065B     Target:  GITR

Application:  Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

Biosimilar reference antibodies

Biotinylated Anti-ADAM9 (biosimilar) mAb

SKU:  BME100064B     Target:  ADAM9

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100048B     Target:  Her2

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

Biosimilar reference antibodies

Biotinylated Anti-CCR8(10A11) mAb

SKU:  BME100063B     Target:  CCR8

Application:  ELISA, Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100050B     Target:  CD47

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100075B     Target:  CLDN18.2

Application:  Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100074B     Target:  ITGA4

Application:  Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100072B     Target:  GPRC5D

Application:  Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100058B     Target:  TNFSF11

Application:  Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

Biosimilar reference antibodies

Biotinylated Anti-LAG3 (relatlimab biosimilar)mAb

SKU:  BME100062B     Target:  LAG3

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100061B     Target:  VEGFA

Application:  ELISA

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100060B     Target:  VEGFR2

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

Biosimilar reference antibodies

Biotinylated Anti-HER3 (patritumab biosimilar)mAb

SKU:  BME100057B     Target:  HER3

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

Biosimilar reference antibodies

Biotinylated Anti-TNFa(Adalimumab biosimilar) mAb

SKU:  BME100056B     Target:  TNFA

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100055B     Target:  CSF1R

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

Biosimilar reference antibodies

Biotinylated Anti-BTLA (icatolimab biosimilar)mAb

SKU:  BME100054B     Target:  BTLA

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

Biosimilar reference antibodies

Biotinylated Anti-OX40( ivuxolimab biosimilar)mAb

SKU:  BME100053B     Target:  OX40

Application:  Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100052B     Target:  IL4RA

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100051B     Target:  CD19

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100046B     Target:  CD37

Application:  Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100045B     Target:  BAFF-R

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00