Biosimilar參照抗體

在生物藥研發(fā)中，抗體藥物研發(fā)無疑是最受關注的焦點，是增長最快的細分領域之一，已成為生物藥中最重要的一大品類。在抗體藥物開發(fā)過程中，頭對頭的質(zhì)量可比性研究更是重中之重。通常臨床階段及上市抗體藥分子是大家首選的對標參照。

締碼生物功能活性蛋白表達平臺利用HEK293哺乳動物細胞分泌表達系統(tǒng)，重組表達了眾多熱門靶點的biosimilar參照抗體，便利廣大科研工作者進行相關開發(fā)過程中的對比研究，同時也可以輔佐驗證靶點蛋白的功能活性。

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產(chǎn)品數(shù)據(jù)展示：

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活性蛋白檢測

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Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human PD1, mFc-His tagged protein (PME100025) can bind Anti-PD-1 Neutralizing antibody in a linear range of 0.24-6.49 ng/ml.

流式功能檢測對比

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Figure 2. HEK293 cell line transfected with irrelevant protein and human PD1 were surface stained with anti-PD1 neutralizing antibody 1μg/ml (pembrolizumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.

Biosimilar參照抗體列表

Biosimilar reference antibodies

Biotinylated Anti-SARS-CoV-2 (CB6 biosimilar) mAb

SKU:  BME100011B     Target:  SARS

Application:  ELISA

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100010B     Target:  B7-H3

Application:  ELISA

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100009B     Target:  PDL1

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

Biosimilar reference antibodies

Biotinylated Anti-TIM3 (cobolimab biosimilar) mAb

SKU:  BME100008B     Target:  TIM3

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

Biosimilar reference antibodies

Biotinylated Anti-IL6 (siltuximab biosimilar) mAb

SKU:  BME100007B     Target:  IL6

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100005B     Target:  CD70

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100004B     Target:  CD38

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100003B     Target:  CD123

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

Biosimilar reference antibodies

Biotinylated Anti-CS1 (elotuzumab biosimilar) mAb

SKU:  BME100002B     Target:  CS1

Application:  ELISA; Flow Cyt

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

SKU:  BME100001B     Target:  CD47

Application:  ELISA

Price: 50 μg ￥890.00 ; 100 μg ￥1699.00

Biosimilar reference antibodies

Anti-HEL Human IgG4-Kappa Isotype control mAb

SKU:  BME100212     Target:  HEL

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-HEL Human IgG2-Kappa Isotype control mAb

SKU:  BME100211     Target:  HEL

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-HEL Human IgG1-Kappa Isotype control mAb

SKU:  BME100210     Target:  HEL

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00