Biosimilar參照抗體

在生物藥研發(fā)中，抗體藥物研發(fā)無(wú)疑是最受關(guān)注的焦點(diǎn)，是增長(zhǎng)最快的細(xì)分領(lǐng)域之一，已成為生物藥中最重要的一大品類。在抗體藥物開發(fā)過(guò)程中，頭對(duì)頭的質(zhì)量可比性研究更是重中之重。通常臨床階段及上市抗體藥分子是大家首選的對(duì)標(biāo)參照。

締碼生物功能活性蛋白表達(dá)平臺(tái)利用HEK293哺乳動(dòng)物細(xì)胞分泌表達(dá)系統(tǒng)，重組表達(dá)了眾多熱門靶點(diǎn)的biosimilar參照抗體，便利廣大科研工作者進(jìn)行相關(guān)開發(fā)過(guò)程中的對(duì)比研究，同時(shí)也可以輔佐驗(yàn)證靶點(diǎn)蛋白的功能活性。

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產(chǎn)品數(shù)據(jù)展示：

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活性蛋白檢測(cè)

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Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human PD1, mFc-His tagged protein (PME100025) can bind Anti-PD-1 Neutralizing antibody in a linear range of 0.24-6.49 ng/ml.

流式功能檢測(cè)對(duì)比

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Figure 2. HEK293 cell line transfected with irrelevant protein and human PD1 were surface stained with anti-PD1 neutralizing antibody 1μg/ml (pembrolizumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.

Biosimilar參照抗體列表

SKU:  BME100052P     Target:  IL4RA

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100051P     Target:  CD19

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100046P     Target:  CD37

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100044P     Target:  BAFF

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100043P     Target:  IL2RA

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100042P     Target:  CD40 Ligand

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100041P     Target:  IL6R

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100037P     Target:  4-1BB

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100036P     Target:  ICAM-1

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100035P     Target:  CEACAM5

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100038P     Target:  IL17RA

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100034P     Target:  EGFR

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100033P     Target:  AXL

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100032P     Target:  TNFRSF10B

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100031P     Target:  TweakR

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100030P     Target:  CD52

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100029P     Target:  CD22

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100028P     Target:  BCMA

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100027P     Target:  TIGIT

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100026P     Target:  TIGIT

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100025P     Target:  CD20

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100040P     Target:  CA9

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100039P     Target:  NKG2D

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100024P     Target:  TIGIT

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100022P     Target:  CTLA-4

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100021P     Target:  MSLN

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100020P     Target:  CD40

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100019P     Target:  EPHA3

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100018P     Target:  CD27

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100017P     Target:  CD30

Application:  Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-BCMA (biosimilar) mAb

SKU:  BME100016P     Target:  BCMA

Application:  Flow Cyt

Price: 100 test ￥1360.00

SKU:  BME100015P     Target:  CD33

Application:  Flow Cyt

Price: 100 test ￥1360.00