Biosimilar參照抗體

在生物藥研發(fā)中，抗體藥物研發(fā)無疑是最受關(guān)注的焦點(diǎn)，是增長(zhǎng)最快的細(xì)分領(lǐng)域之一，已成為生物藥中最重要的一大品類。在抗體藥物開發(fā)過程中，頭對(duì)頭的質(zhì)量可比性研究更是重中之重。通常臨床階段及上市抗體藥分子是大家首選的對(duì)標(biāo)參照。

締碼生物功能活性蛋白表達(dá)平臺(tái)利用HEK293哺乳動(dòng)物細(xì)胞分泌表達(dá)系統(tǒng)，重組表達(dá)了眾多熱門靶點(diǎn)的biosimilar參照抗體，便利廣大科研工作者進(jìn)行相關(guān)開發(fā)過程中的對(duì)比研究，同時(shí)也可以輔佐驗(yàn)證靶點(diǎn)蛋白的功能活性。

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產(chǎn)品數(shù)據(jù)展示：

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活性蛋白檢測(cè)

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Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human PD1, mFc-His tagged protein (PME100025) can bind Anti-PD-1 Neutralizing antibody in a linear range of 0.24-6.49 ng/ml.

流式功能檢測(cè)對(duì)比

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Figure 2. HEK293 cell line transfected with irrelevant protein and human PD1 were surface stained with anti-PD1 neutralizing antibody 1μg/ml (pembrolizumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.

Biosimilar參照抗體列表

Biosimilar reference antibodies

Anti-IL7RA(lusvertikimab biosimilar) mAb

SKU:  BME100084     Target:  IL7RA

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-GPC3(codrituzumab biosimilar) mAb

SKU:  BME100083     Target:  GPC3

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-CLDN6 (IMAB027) mAb

SKU:  BME100082     Target:  CLDN6

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-B7-H2(prezalumab biosimilar) mAb

SKU:  BME100081     Target:  B7-H2

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-TSHR (K1-70) mAb

SKU:  BME100080     Target:  TSHR

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-TSHR (M22) mAb

SKU:  BME100079     Target:  TSHR

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-B7-H4(alsevalimab biosimilar) mAb

SKU:  BME100078     Target:  B7H4

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-SELP(crizanlizumab biosimilar) mAb

SKU:  BME100077     Target:  SELP

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-DLL3(Rovalpituzumab biosimilar) mAb

SKU:  BME100068     Target:  DLL3

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-GITR(ragifilimab biosimilar) mAb

SKU:  BME100065     Target:  GITR

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-CCR8(10A11) mAb

SKU:  BME100063     Target:  CCR8

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-CLDN18.2 (zolbetuximab biosimilar) mAb

SKU:  BME100075     Target:  CLDN18.2

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-ITGA4 (natalizumab biosimilar) mAb

SKU:  BME100074     Target:  ITGA4

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-TNFSF11 (denosumab biosimilar)mAb

SKU:  BME100058     Target:  TNFSF11

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-LAG3 (relatlimab biosimilar)mAb

SKU:  BME100062     Target:  LAG3

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-VEGFA(bevacizumab biosimiar) mAb

SKU:  BME100061     Target:  VEGFA

Application:  ELISA

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-VEGFR2 (ramucirumab biosimilar)mAb

SKU:  BME100060     Target:  VEGFR2

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-TNFa(Adalimumab biosimilar) mAb

SKU:  BME100056     Target:  TNFA

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-BTLA (icatolimab biosimilar)mAb

SKU:  BME100054     Target:  BTLA

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-OX40( ivuxolimab biosimilar)mAb

SKU:  BME100053     Target:  OX40

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-IL-4RA (dupilumab biosimilar)mAb

SKU:  BME100052     Target:  IL4RA

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-CD19 (inebilizumab biosimilar)mAb

SKU:  BME100051     Target:  CD19

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-BAFFR (ianalumab biosimilar) mAb

SKU:  BME100045     Target:  BAFF-R

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-BAFF (belimumab biosimilar) mAb

SKU:  BME100044     Target:  BAFF

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-IL2RA (basiliximab biosimilar) mAb

SKU:  BME100043     Target:  IL2RA

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-CD40 Ligand (ruplizumab biosimilar) mAb

SKU:  BME100042     Target:  CD40 Ligand

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-IL6R (tocilizumab biosimilar) mAb

SKU:  BME100041     Target:  IL6R

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-4-1BB (utomilumab biosimilar) mAb

SKU:  BME100037     Target:  4-1BB

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-ICAM-1 (bersanlimab biosimilar) mAb

SKU:  BME100036     Target:  ICAM-1

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-IL17RA (brodalumab biosimilar) mAb

SKU:  BME100038     Target:  IL17RA

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-TweakR (enavatuzumab biosimilar) mAb

SKU:  BME100031     Target:  TweakR

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-CD52 (alemtuzumab biosimilar) mAb

SKU:  BME100030     Target:  CD52

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00